Exposure to Indoor Endocrine-Disrupting Chemicals and Childhood Asthma and Obesity

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Childhood obesity and endocrine disrupting chemicals

The prevalence of obesity around the world has increased sharply. Strong evidence has emerged over the last decades that human exposure to numerous endocrine disrupting chemicals (EDCs) is the cause of obesity and obesity-related metabolic diseases. Many EDCs are manmade chemicals that are released into the environment. EDCs are exogenous compounds that interfere with hormonal regulation and no...

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Exposure to Endocrine Disrupting Chemicals and Male Reproductive Health

Endocrine disrupting chemicals (EDCs) can interfere with normal hormonal balance and may exert adverse consequences on humans. The male reproductive system may be susceptible to the effects of such environmental toxicants. This review discusses the recent progress in scientific data mainly from epidemiology studies on the associations between EDCs and male reproductive health and our understand...

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Endocrine disrupting chemicals in indoor and outdoor air.

The past 50 years have seen rapid development of new building materials, furnishings, and consumer products and a corresponding explosion in new chemicals in the built environment. While exposure levels are largely undocumented, they are likely to have increased as a wider variety of chemicals came into use, people began spending more time indoors, and air exchange rates decreased to improve en...

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Developmental exposure to endocrine-disrupting chemicals programs for reproductive tract alterations and obesity later in life.

Many chemicals in the environment, especially those with estrogenic activity, are able to disrupt the programming of endocrine signaling pathways established during development; these chemicals are referred to as endocrine-disrupting chemicals. Altered programming can result in numerous adverse consequences in estrogen-target tissues, some of which may not be apparent until later in life. For e...

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Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union.

CONTEXT Obesity and diabetes are epidemic in the European Union (EU). Exposure to endocrine-disrupting chemicals (EDCs) is increasingly recognized as a contributor, independent of diet and physical activity. OBJECTIVE The objective was to estimate obesity, diabetes, and associated costs that can be reasonably attributed to EDC exposures in the EU. DESIGN An expert panel evaluated evidence f...

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2020

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2020-023861u